Author: Alex Yang
Editors: Ethan Tai, Miriam Heikal
Artist: Lalita Ma

The growing emphasis on environmental sustainability has accelerated progress in green chemistry, particularly in developing green solvents and sustainable chemical processes. Traditional solvents used in large-scale industries like pharmaceuticals, agriculture, and manufacturing contribute to pollution, health risks, and resource depletion. Most conventional solvents are usually VOCs, leading to air and water pollution and carrying hazardous waste hazards. Green solvents have emerged to meet such issues, presented as benign media that will minimize environmental impact without compromising the efficiency of chemical reactions.
Green solvents are normally derived from renewable resources or have properties that reduce environmental and health hazards. They contribute to sustainability by lowering toxicity, reducing energy consumption, and enhancing biodegradability. Water, one of the most recognized green solvents, is nontoxic and widely available, making it a universal solvent for reactions and processes without recycling. Ionic liquids, known for their non-volatile properties, have the potential to be tailor-made for various substances to provide good dissolution capacities without emitting gaseous emanations. Supercritical fluids, above all supercritical carbon dioxide, have attracted significant interest in many extraction and synthesis processes due to the possibility of substitution with toxic organic solvents using their recyclable, environmentally harmless properties. On top of using bio-based solvent alternatives like bioethanol of plant origin, glycerol further reduces the economy's dependence on fossil-fuel-sourced chemicals.

Adopting green solvents in chemical processes will provide numerous advantages, including reduced environmental impact, improved safety, and observance of the most drastic rules and regulations. Through this process, industries can minimize the use of harmful substances, making the production process more ecological and reducing waste disposal costs. Besides, green solvents often improve reaction efficiency and selectivity, leading to greener and more economic manufacturing. For example, in the pharmaceutical industry, green solvents help reduce toxic by-products, making drugs safer and more efficient. Similarly, supercritical carbon dioxide is a safer alternative to harmful organic solvents used for decaffeination and extracting essential oils in food processing.
Despite these associated benefits, challenges remain in the wide-scale application of green solvents. The preparation of some bio-based or ionic liquid solvents remains expensive, and their large-scale application requires further research into their long-term stability, toxicity, and recyclability. Besides, the transition from conventional to greener solvents may require changes in processes and new technologies, which can be costly and time-consuming. The economic feasibility of green solvents needs further investigation to ensure accessibility for industries of all sizes, particularly the small and medium enterprises that may lack the financial capacity to invest in large-scale process changes.

As research in green chemistry continues to advance, the development of more efficient, cost-effective, and widely applicable green solvents is expected to accelerate. This process makes sustainable chemical processes more accessible across various industrial areas. Innovations in green solvent design, catalysis, and process optimization are advancing rapidly. At the same time, government regulations and growing consumer demand for sustainability are driving further investment in greener alternatives. These can be further enhanced with other emerging technologies, including nanotechnology and biocatalysis.
While challenges remain, transitioning to green solvents is one crucial step toward long-term sustainability in the chemical industries. Green solvents can lead to a cleaner, safer, and more sustainable future. Achieving this goal requires sustained collaboration among researchers, policymakers, and industrial leaders to establish green solvents as the standard in chemical manufacturing and ensure a shift toward greener, economically viable production methods.
Citations:
Anastas, P. T., and J. C. Warner. Green Chemistry: Theory and Practice. Oxford University
Press, 1998.
Byrne, F. P., et al. "Tools and Techniques for Solvent Selection: Green Solvent Selection
Guides." Sustainable Chemical Processes, vol. 4, no. 1, 2016, p. 7.
Clarke, C. J., et al. "Green and Sustainable Solvents in Chemical Processes." Chemical Reviews,
vol. 118, no. 2, 2018, pp. 747–800.
Kerton, F. M., and R. Marriott. Alternative Solvents for Green Chemistry. 2nd ed., Royal Society
of Chemistry, 2013.
Sheldon, R. A. "Atom Utilisation, E Factors and the Catalytic Solution." Comptes Rendus de
l'Académie des Sciences - Series IIC - Chemistry, vol. 3, no. 7–8, 2000, pp. 541–551.
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